Matrix metalloproteinases and the regulation of tissue remodelling
نویسندگان
چکیده
منابع مشابه
Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling.
Fibrillin is the principal structural component of the 10-12 nm diameter elastic microfibrils of the extracellular matrix. We have previously shown that both fibrillin molecules and assembled microfibrils are susceptible to degradation by serine proteases. In this study, we have investigated the potential catabolic effects of six matrix metalloproteinases (MMP-2, MMP-3, MMP-9, MMP-12, MMP-13 an...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2007
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm2125